Growth Hormone 1 anticorps (AA 27-217)

N° du produit ABIN3042795

Cet anticorps anti-Growth Hormone 1 est un anticorps Lapin Polyclonal détectant Growth Hormone 1 dans IHC, WB et ELISA. Adapté pour Humain.

Aperçu rapide pour Growth Hormone 1 anticorps (AA 27-217) (ABIN3042795)

Antigène: Growth Hormone 1 (GH1)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Growth Hormone 1 est non-conjugé

Application: Immunohistochemistry (IHC), Western Blotting (WB), ELISA

Détail du produit anti-Growth Hormone 1 anticorps

Épitope: AA 27-217

Fonction: Anti-Growth Hormone/GH1 Antibody Picoband®

Réactivité croisée (Details): No cross-reactivity with other proteins

Attributs du produit: Anti-Growth Hormone/GH1 Antibody (ABIN3042795). Tested in ELISA, IHC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogène: E. coli-derived human GH recombinant protein (Position: F27-F217).

Isotype: IgG

Information d'application

Indications d'application: ELISA, 0.1-0.5 μg/mL, -
Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human
Western blot, 0.1-0.5 μg/mL, Human
1. Niall, H. D., Hogan, M. L., Sauer, R., Rosenblum, I. Y., Greenwood, F. C. : Sequence of pituitary and placental lactogenic and growth hormones: evolution from a primordial peptide by gene reduplication. Proc. Nat. Acad. Sci. 68: 866-869, 1971. 2. Sundstrom, M., Lundqvist, T., Rodin, J., Giebel, L. B., Milligan, D., Norstedt, G. : Crystal structure of an antagonist mutant of human growth hormone, G120R, in complex with its receptor at 2.9 angstrom resolution. J. Biol. Chem. 271: 32197-32203, 1996.

Commentaires:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide. Carrier free (No BSA)

Agent conservateur: Sodium azide, Without preservative

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Détails sur Growth Hormone 1

Antigène: Growth Hormone 1 (GH1)

Autre désignation: GH1

Sujet:

Synonyms: Somatotropin,Growth hormone,GH,GH-N,Growth hormone 1,Pituitary growth hormone,GH1,

Background: Growth Hormone (GH) is mapped to 17q22-q24. Growth hormone (GH) is synthesized by acidophilic or somatotropic cells of the anterior pituitary gland. Human growth hormone has a molecular mass of 22,005 and contains 191 amino acid residues with 2 disulfide bridges. It binds two receptor molecules and thereby induces signal transduction through receptor dimerization. At high concentrations, GH acts as an antagonist because of a large difference in affinities at the respective binding sites.

Sequence Similarities: Belongs to the somatotropin/prolactin family.

Poids moléculaire: 22 kDa

UniProt: P01241

Pathways: Signalisation NF-kappaB, Signalistation JAK/STAT, Intracellular Steroid Hormone Receptor Signaling Pathway, Peptide Hormone Metabolism, Regulation of Intracellular Steroid Hormone Receptor Signaling, Regulation of Hormone Metabolic Process, Response to Growth Hormone Stimulus, Regulation of Hormone Biosynthetic Process